Stimulating effect of gold trichloride on DNA synthesis of human lymphoid cells.
نویسنده
چکیده
The effect of gold trichloride on DNA synthesis of human thymocytes and peripheral blood lymphocytes was tested. A stimulation was obtained in both cell types with a concentration of 6-50 micrograms/ml. Gold trichloride may thus not be used in a lymphocyte transformation test for the diagnosis of contact allergy.
منابع مشابه
Microsoft Word - IAA459BF
The effect of gold trichloride on DNA synthesis of human thymocytes and peripheral blood lymphocytes was tested. A stimulation was obtained in both cell types with a concentration of 6–50 μg/ml. Gold trichloride may thus not be used in a lymphocyte transformation test for the diagnosis of contact allergy. Correspondence to: Dr. Klas Nordlind, Department of Dermatology, Karolinska Sjukhuset, S–1...
متن کاملThe Effect of 6-Thioguanine on Proliferation, Viability and Expression of the Genes DNMT 3A, DNMT 3B and HDAC3 in Lymphoid Cancer Cell Line Nalm6
Background: 6-thioguanine (6-TG) is one of the thiopurine drugs with successful use in oncology, especially for acute lymphoblastic leukemia (ALL). 6-TG is proposed to act as an epigenetic drug affecting DNA methylation. The aim of this study was to clarify the effect of 6-TG on the proliferation, viability and expression of genes coding for the enzymes DNA methyltransferase 3A and DNA methyltr...
متن کاملSupportive Effects of Human Embryonic Fibroblast Cell Lines on Growth and Proliferation of EBV-Transformed Lymphoblastoid Cells
Human diploid fibroblast cells produce a spectrum of necessary growth factors and extracellular matrix (ECM) components essential for growth and proliferation of a variety of other cell types. In this study, the effect of five human embryonic fibroblast cell lines, isolated from liver, lung, skin and foreskin tissues, was investigated. A coculture system analyse was employed to cloning efficien...
متن کاملGnidilatimonoein from Daphne mucronata inhibits DNA synthesis in human cancer cell lines
The anticancer agents from plant sources usually exert their action through a wide range of mechanisms. As part of our studies of plants for new anticancer agents with emphasis on Thymelaeaceae family, we examined the cytotoxicity and anti-tumor activity of the water extract of D. mucronata leaves against induced breast tumor in rats. In the current study, we were interested to obtain some know...
متن کاملGnidilatimonoein from Daphne mucronata inhibits DNA synthesis in human cancer cell lines
The anticancer agents from plant sources usually exert their action through a wide range of mechanisms. As part of our studies of plants for new anticancer agents with emphasis on Thymelaeaceae family, we examined the cytotoxicity and anti-tumor activity of the water extract of D. mucronata leaves against induced breast tumor in rats. In the current study, we were interested to obtain some know...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- International archives of allergy and applied immunology
دوره 77 4 شماره
صفحات -
تاریخ انتشار 1985